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Alternative Splicing Gallery

Detail view for swissprot protein MK08_HUMAN and isoform P45983-3

Template: 2g01
Sequence Identity (Template - Swissprot): 0.994382
Coverage of swissprot protein: 0.83372366

Alignment

MK08_HUMAN	MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEE
2g01		--------NFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEE
SSE		--------CCEEEECCCCEEEECCCCCCCCEEEECCCEEEECCEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCECCEEEEECCCCCCCC
VARSPLIC	                                                                                                    

MK08_HUMAN	FQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGM
2g01		FQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMEPEVVTRYYRAPEVILGM
SSE		CCCEEEEEECCCEEHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHEEECCCCCEEECCCCCCEECCCCCCCCCCCCCHHHCCHHHHCCC
VARSPLIC	                                                                                                    

MK08_HUMAN	GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
2g01		GYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
SSE		CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHCCCCCC
VARSPLIC	       R          RRRRRRRRRRRR                                                                      

MK08_HUMAN	MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVS
2g01		MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLE------------------------------------
SSE		CCCCCCCCCCCHHHHCCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC------------------------------------
VARSPLIC	                                                                                                    

MK08_HUMAN	SMSTDPTLASDTDSSLEAAAGPLGCCR
2g01		---------------------------
SSE		---------------------------
VARSPLIC

Varsplic events:
VSP_004832 REPLACE 219-230 VCHKILFPGRDY => IKGGVLFPGTDH, affected aminoacids in template: 210-221 Color: Green
VSP_004831 REPLACE 208-208 L => I, affected aminoacids in template: 199-199 Color: Green

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