Detail view for swissprot protein ACV1B_HUMAN and isoform P36896-2
Template: 1b6c
Sequence Identity (Template - Swissprot): 0.7410926
Coverage of swissprot protein: 0.83366334
Alignment
ACV1B_HUMAN MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVR--TCIPK-VELVPAGK----------PF-YCLS 1b6c -------------------------------------------------GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLG SSE -------------------------------------------------CEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCEEEEHHHHCCCEEEECC VARSPLIC ACV1B_HUMAN SEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPS-MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYD 1b6c KQEV------IRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF------------------DVELLKLE-----------TTLKDLIYD SSE CCCC------CHHHHHHHHHCCCCCEEEEEECHHHCCCCCCECCCECCCCCEEE------------------EEEEEEEC-----------CCHHHHHHH VARSPLIC ACV1B_HUMAN LSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYH 1b6c MTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYH SSE CCCCCCCCCCCHHHHHHHHHHCEEEEEEEEECCEEEEEEEECCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCECCEEEEEECCCCCCCCEEEEECCC VARSPLIC ACV1B_HUMAN EHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEV 1b6c EHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEV SSE CCCEHHHHHHHCCECHHHHHHHHHHHHHHHHHHHCCECCCCCECEEECCCCCHHHEEECCCCCEEECCCCCCEEEECCCCEEEECCCCCCCCHHHCCHHH VARSPLIC ACV1B_HUMAN LDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARL 1b6c LDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARL SSE HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCECECCECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHCC VARSPLIC SSSSSSSSSSSSSSSSSSSSS ACV1B_HUMAN TALRIKKTLSQLSVQED-VKI------------------------------------------------------------------------------- 1b6c TALRIKKTLSQLSQQEGGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYG SSE CHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCEEEEHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECHHHCCC VARSPLIC SSSSSSSSSSSSSSSSSSSSS ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c ATGHPGIIPPHATLVFDVELLKLETTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ SSE CCCECCCECCCCCEEEEEEEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCEEEEEEEEECCEEEEEEEECCEEEEEEEECHHHHHHHHHHHHHHH VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIA SSE HCCCCCCCECCEEEEEECCCCCCCCEEEEECCCCCCEHHHHHHHCCECHHHHHHHHHHHHHHHHHHHCCECCCCCECEEECCCCCHHHEEECCCCCEEEC VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c DLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKL SSE CCCCCEEEECCCCEEEECCCCCCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCECECCECCCCCCCCCCCCCCCCCHHHHHHHHCCCCC VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c RPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFML SSE CCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCEEEEHHHHCCCEEEEC VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c GKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLETTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFG SSE CCCCCCHHHHHHHHHCCCCCEEEEEECHHHCCCCCCECCCECCCCCEEEEEEEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCEEEEEEEEECCE VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c EVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLH SSE EEEEEEECCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCECCEEEEEECCCCCCCCEEEEECCCCCCEHHHHHHHCCECHHHHHHHHHHHHHHHHHHH VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c MEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSI SSE CCECCCCCECEEECCCCCHHHEEECCCCCEEECCCCCCEEEECCCCEEEECCCCCCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCECE VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c GGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGGVQVETISPGDGRTFPK SSE CCECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c RGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLETTLKDLIYDM SSE CCCEEEEEEEEEECCCCEEEEHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECHHHCCCCCCECCCECCCCCEEEEEEEEEECCCHHHHHHHC VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c TTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHE SSE CCCCCCCCCCHHHHHHHHHHCEEEEEEEEECCEEEEEEEECCEEEEEEEECHHHHHHHHHHHHHHHHCCCCCCCECCEEEEEECCCCCCCCEEEEECCCC VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c HGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVL SSE CCEHHHHHHHCCECHHHHHHHHHHHHHHHHHHHCCECCCCCECEEECCCCCHHHEEECCCCCEEECCCCCCEEEECCCCEEEECCCCCCCCHHHCCHHHH VARSPLIC ACV1B_HUMAN ---------------------------------------------------------------------------------------------------- 1b6c DDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLT SSE CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCECECCECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHCCC VARSPLIC ACV1B_HUMAN ---------------- 1b6c ALRIKKTLSQLSQQEG SSE HHHHHHHHHHHHHCCC VARSPLIC
Varsplic events:
VSP_004954 REPLACE 465-505 ALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI => VRSWPPAAFPSA, affected aminoacids in template: 395-436 Color: Pink