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Alternative Splicing Gallery

Detail view for swissprot protein LIS1_HUMAN and isoform P43034-2

Template: 1vyh
Sequence Identity (Template - Swissprot): 0.9935484
Coverage of swissprot protein: 0.7579462

Alignment

LIS1_HUMAN	VLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEK
1vyh		------------------------------------------------------------------------------------------KEWIPRPPEK
SSE		------------------------------------------------------------------------------------------CCCCCCCCCC
VARSPLIC	                                                                                                    

LIS1_HUMAN	YALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIM
1vyh		YALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVSIM
SSE		EEEECCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCEEECCCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCCCEEECCCCCCCCEEEEEEC
VARSPLIC	                                DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD                               

LIS1_HUMAN	PNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSET
1vyh		PNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHRHVVECISWAPESSYSSISEATGSE-
SSE		CCCCEEEEEECCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCEEEEECCCCCCECCCCECCCCHHHHHHHCCCCC-
VARSPLIC	                                   RDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

LIS1_HUMAN	KKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVD
1vyh		------GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVD
SSE		------CCEECCCECCCCEEEEECCCCEEEEEECCCCCCCCEECCCCCCCEEEEECCCCCEEEEECCCCCCCEEECCCCCCEEEEEECCCCCCEEEEECC
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

LIS1_HUMAN	QTVKVWECR
1vyh		QTVKVWE--
SSE		CEEEEEC--
VARSPLIC	DDDDDDD

Varsplic events:
VSP_019378 REPLACE 236-236 V => I, affected aminoacids in template: 145-145 Color: Green
VSP_019379 REMOVE 237-409, affected aminoacids in template: 146-309 Color: Red
VSP_019377 REMOVE 133-169, affected aminoacids in template: 42-78 Color: Red

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